The International Arab Journal of Information Technology (IAJIT)


Classification of Acute Leukaemia Cells using Multilayer Perceptron and Simplified Fuzzy

 Leukaemia is a cancer of blood that causes more dea th than any other cancers among children and young adults under the age of 20. This disease can be cured if i t is detected and treated at the early stage. Based on this argument, the requirement for fast analysis of blood cells for le ukaemia is of paramount importance in the healthcar e industry. This paper presents the classification of White Blood Cells (W BC) inside the Acute Lymphoblastic Leukaemia (ALL) and Acute Myelogenous Leukaemia blood samples by using the Mu ltilayer Perceptron (MLP) and Simplified Fuzzy ARTMAP (SFAM) neural networks. Here, the WBC will be classified a s lymphoblast, myeloblast and normal cell for the purpose of categorization of acute leukaemia types. Two differ ent training algorithms namely Levenberg3Marquardt and Bayesian Regulation algorithms have been employed to train t he MLP network. There are a total of 42 input features that consist of the size, shape and colour based features, have been ex tracted from the segmented WBCs, and used as the ne ural network inputs for the classification process. The classification results indicating that all networks have produced good classification performance for the overall proposed features. Howe ver, the MLP network trained by Bayesian Regulation algorithm has produced the best classification performance with t esting accuracy of 95.70% for the overall proposed features. Thus, the results significantly demonstrate the suitability o f the proposed features and classification using ML P and SFAM networks for classifying the acute leukaemia cells in blood samp le.    

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[25] Venkatesan P. and Suresh M., Classification of Renal Failure Using Simplified Fuzzy Adaptive Resonance Theory Map, International Journal of Computer Science and Network Security , vol. 9, no. 11, pp. 129-134, 2009. Aimi Abdul Nasir received her B.Eng (Hons) degree in Mechatronic Engineering from Universiti Malaysia Perlis in 2009 and MSc in Biomedical Electronic Engineering from the Universiti Malaysia Perlis, in 2011. Currently, she is pursuing her PhD in Biomedical Electronic Engineering at UniMAP. Her research interests include image processing, medical image analysis, artificial neur al network and medical diagnostic system. Mohd Yusoff Mashor obtained his B.Eng. degree in control and computer engineering from University of Westminster, London in 1990. Under Universiti Sains Malaysia RLKA scheme, he pursued his MSc in control engineering and information technology at University of Sheffield in 1991. In 1995, he obtained his PhD specialized in neural network from University of Sheffield. He started his service in USM in the School of Electrical and Electronic Engineering in December 1995. He is currently the Dean of Postgraduate Studies, Universiti Malaysia Perlis. He has developed his expertise in neural network, system identification, fuzzy logic, control system, intelligent forecasting/prediction, image processing and medical diagnostic systems. He has authored and co-authored for more than 100 research publications in the form of book chapters, refereed journals and conferences at the international and national levels. Rosline Hassan obtained her medical degree, MD from Universiti Kebangsaan Malaysia and MMed in Pathology from Universiti Sains Malaysia. She is currently the head of the Department of Hematology, School of Medical Sciences, Universiti Sains Malaysia. Her research interests include haematopathology with special interest in molecular aspect of haematologi cal disorders, leukaemias and myeloproliferative disorders, red cell disorders inclusive of thalasse mia, cytogenetic of leukaemia, cell culture studies and stem cell studies. She has published numerous research articles in the international journals and conferen ce proceedings.